Characterization of Rabbit Corneas Subjected to Stromal Stiffening by the Açaí Extract (Euterpe oleracea)

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dc.contributor.authorBersanetti P.A.
dc.contributor.authorBueno T.L.N.
dc.contributor.authorMorandim-Giannetti A.A.
dc.contributor.authorNogueira R.F.
dc.contributor.authorMatos J.R.
dc.contributor.authorSchor P.
dc.date.accessioned2019-08-20T00:12:01Z
dc.date.available2019-08-20T00:12:01Z
dc.date.issued2017
dc.description.abstract© 2016 Taylor & Francis.Purpose: In this study, we characterized rabbit corneas subjected to corneal cross-linking (CXL) with açaí extract compared with a riboflavin photo-stimulated procedure. Materials and Methods: The corneas of the slaughterhouse rabbits were divided into three groups: control, consisting of untreated corneal samples; riboflavin/UVA, where corneas were treated with 0.1% riboflavin photo-stimulated at 365 nm as the standard protocol; and açaí, where the samples were subjected to 4% açaí extract for 0.5–2 h. After the CXL procedure, corneas of the three groups were characterized by analyzing their elastic modulus and thermal denaturation profile. Results: The elastic modulus at 3% strain showed an approximately threefold increase in the riboflavin/UVA group and 10.5 times in the corneas treated with 4% açaí extract for 2 h, compared with the control group (p < 0.01). The denaturation temperature values of the two groups of crosslinked corneas increased significantly (p < 0.05) and were more pronounced in the açaí group. Conclusions: The açaí extract was effective in promoting CXL in rabbit corneas as characterized by the different techniques.
dc.description.firstpage528
dc.description.issuenumber4
dc.description.lastpage533
dc.description.volume42
dc.identifier.citationBERSANETTI, P. A.; BUENO, T. L. N.; GIANNETTI, Andreia de Araujo Morandim; NOGUEIRA, R. F.; MATOS, J. R.; SCHOR, P.. Characterization of Rabbit Corneas Subjected to Stromal Stiffening by the Açaí Extract ( ). Current Eye Research (Print), n. -, p. 1-6, 2016.
dc.identifier.doi10.1080/02713683.2016.1214970
dc.identifier.issn1460-2202
dc.identifier.urihttps://repositorio.fei.edu.br/handle/FEI/1687
dc.relation.ispartofCurrent Eye Research
dc.rightsAcesso Restrito
dc.subject.otherlanguageAçaí extract
dc.subject.otherlanguagecorneal crosslinking
dc.subject.otherlanguagedifferential scanning calorimetry
dc.subject.otherlanguageelastic modulus
dc.subject.otherlanguagekeratoconus
dc.subject.otherlanguageriboflavin
dc.titleCharacterization of Rabbit Corneas Subjected to Stromal Stiffening by the Açaí Extract (Euterpe oleracea)
dc.typeArtigo
fei.scopus.citations8
fei.scopus.eid2-s2.0-84986184077
fei.scopus.subjectAnimals
fei.scopus.subjectCollagen
fei.scopus.subjectCornea
fei.scopus.subjectCorneal Stroma
fei.scopus.subjectCross-Linking Reagents
fei.scopus.subjectElastic Modulus
fei.scopus.subjectEuterpe
fei.scopus.subjectPhotochemotherapy
fei.scopus.subjectPhotosensitizing Agents
fei.scopus.subjectPhytotherapy
fei.scopus.subjectPlant Extracts
fei.scopus.subjectRabbits
fei.scopus.subjectRiboflavin
fei.scopus.subjectUltraviolet Rays
fei.scopus.updated2024-03-04
fei.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84986184077&origin=inward
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