Characterization of Rabbit Corneas Subjected to Stromal Stiffening by the Açaí Extract (Euterpe oleracea)
dc.contributor.author | Bersanetti P.A. | |
dc.contributor.author | Bueno T.L.N. | |
dc.contributor.author | Morandim-Giannetti A.A. | |
dc.contributor.author | Nogueira R.F. | |
dc.contributor.author | Matos J.R. | |
dc.contributor.author | Schor P. | |
dc.date.accessioned | 2019-08-20T00:12:01Z | |
dc.date.available | 2019-08-20T00:12:01Z | |
dc.date.issued | 2017 | |
dc.description.abstract | © 2016 Taylor & Francis.Purpose: In this study, we characterized rabbit corneas subjected to corneal cross-linking (CXL) with açaí extract compared with a riboflavin photo-stimulated procedure. Materials and Methods: The corneas of the slaughterhouse rabbits were divided into three groups: control, consisting of untreated corneal samples; riboflavin/UVA, where corneas were treated with 0.1% riboflavin photo-stimulated at 365 nm as the standard protocol; and açaí, where the samples were subjected to 4% açaí extract for 0.5–2 h. After the CXL procedure, corneas of the three groups were characterized by analyzing their elastic modulus and thermal denaturation profile. Results: The elastic modulus at 3% strain showed an approximately threefold increase in the riboflavin/UVA group and 10.5 times in the corneas treated with 4% açaí extract for 2 h, compared with the control group (p < 0.01). The denaturation temperature values of the two groups of crosslinked corneas increased significantly (p < 0.05) and were more pronounced in the açaí group. Conclusions: The açaí extract was effective in promoting CXL in rabbit corneas as characterized by the different techniques. | |
dc.description.firstpage | 528 | |
dc.description.issuenumber | 4 | |
dc.description.lastpage | 533 | |
dc.description.volume | 42 | |
dc.identifier.citation | BERSANETTI, P. A.; BUENO, T. L. N.; GIANNETTI, Andreia de Araujo Morandim; NOGUEIRA, R. F.; MATOS, J. R.; SCHOR, P.. Characterization of Rabbit Corneas Subjected to Stromal Stiffening by the Açaí Extract ( ). Current Eye Research (Print), n. -, p. 1-6, 2016. | |
dc.identifier.doi | 10.1080/02713683.2016.1214970 | |
dc.identifier.issn | 1460-2202 | |
dc.identifier.uri | https://repositorio.fei.edu.br/handle/FEI/1687 | |
dc.relation.ispartof | Current Eye Research | |
dc.rights | Acesso Restrito | |
dc.subject.otherlanguage | Açaí extract | |
dc.subject.otherlanguage | corneal crosslinking | |
dc.subject.otherlanguage | differential scanning calorimetry | |
dc.subject.otherlanguage | elastic modulus | |
dc.subject.otherlanguage | keratoconus | |
dc.subject.otherlanguage | riboflavin | |
dc.title | Characterization of Rabbit Corneas Subjected to Stromal Stiffening by the Açaí Extract (Euterpe oleracea) | |
dc.type | Artigo | |
fei.scopus.citations | 8 | |
fei.scopus.eid | 2-s2.0-84986184077 | |
fei.scopus.subject | Animals | |
fei.scopus.subject | Collagen | |
fei.scopus.subject | Cornea | |
fei.scopus.subject | Corneal Stroma | |
fei.scopus.subject | Cross-Linking Reagents | |
fei.scopus.subject | Elastic Modulus | |
fei.scopus.subject | Euterpe | |
fei.scopus.subject | Photochemotherapy | |
fei.scopus.subject | Photosensitizing Agents | |
fei.scopus.subject | Phytotherapy | |
fei.scopus.subject | Plant Extracts | |
fei.scopus.subject | Rabbits | |
fei.scopus.subject | Riboflavin | |
fei.scopus.subject | Ultraviolet Rays | |
fei.scopus.updated | 2024-07-01 | |
fei.scopus.url | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84986184077&origin=inward |