A whole brain morphometric analysis of changes associated with pre-term birth

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dc.contributor.authorCarlos E. Thomaz
dc.contributor.authorBOARDMAN, J. P.
dc.contributor.authorCOUNSELL, S.
dc.contributor.authorHILLS, D. L. S.
dc.contributor.authorHAINAL, J. V.
dc.contributor.authorEDWARD, A. D.
dc.contributor.authorRUTHERFORD, M. A.
dc.contributor.authorGILIES, D. F.
dc.contributor.authorRUECKRT, D.
dc.contributor.authorOrcidhttps://orcid.org/0000-0001-5566-1963
dc.contributor.authorOrcidTHOMAZ, C. E.; BOARDMAN, J. P.; COUNSELL, S.; HILLS, D. L. S.; HAINAL, J. V.; EDWARD, A. D.; RUTHERFORD, M. A. ; GILIES, D. F.; RUECKRT, D. A whole brain morphometric analysis of changes associated with pre-term birth. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 6144 III, n. 61445Y, February, 2006.
dc.date.accessioned2022-01-12T22:05:35Z
dc.date.available2022-01-12T22:05:35Z
dc.date.issued2006-02-13
dc.description.abstractPre-term birth is strongly associated with subsequent neuropsychiatric impairment. To identify structural differences in preterm infants we have examined a dataset of magnetic resonance (MR) images containing 88 preterm infants and 19 term born controls. We have analyzed these images by combining image registration, deformation based morphometry (DBM), multivariate statistics, and effect size maps (ESM). The methodology described has been performed directly on the MR intensity images rather than on segmented versions of the images. The results indicate that the approach described makes clear the statistical differences between the control and preterm samples, showing a leave-one-out classification accuracy of 94.74% and 95.45% respectively. In addition, finding the most discriminant direction between the groups and using DBM features and ESM we are able to identify not only what are the changes between preterm and term groups but also how relatively relevant they are in terms of volume expansion and contraction.
dc.description.volume6144 III
dc.identifier.citationTHOMAZ, C. E.; BOARDMAN, J. P.; COUNSELL, S.; HILLS, D. L. S.; HAINAL, J. V.; EDWARD, A. D.; RUTHERFORD, M. A. ; GILIES, D. F.; RUECKRT, D. A whole brain morphometric analysis of changes associated with pre-term birth. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 6144 III, n. 61445Y, February, 2006.
dc.identifier.doi10.1117/12.651315
dc.identifier.issn1605-7422
dc.identifier.urihttps://repositorio.fei.edu.br/handle/FEI/4349
dc.relation.ispartofProgress in Biomedical Optics and Imaging - Proceedings of SPIE
dc.rightsAcesso Restrito
dc.subject.otherlanguageDeformation-based morphometry
dc.subject.otherlanguageMagnetic resonance images
dc.subject.otherlanguagePattern recognition
dc.subject.otherlanguageStatistical methods
dc.titleA whole brain morphometric analysis of changes associated with pre-term birth
dc.typeArtigo de evento
fei.scopus.citations4
fei.scopus.eid2-s2.0-33745125728
fei.scopus.subjectDeformation based morphometry (BDM)
fei.scopus.subjectEffect size maps (ESM)
fei.scopus.subjectMagnetic resonance images
fei.scopus.subjectNeuropsychiatric impairment
fei.scopus.updated2024-07-01
fei.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33745125728&origin=inward
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