Creative Commons "Este é um artigo publicado em acesso aberto sob uma licença Creative commons (CC BY 4.0). Fonte: https://www.scoporigius.com/inward/record.uri?partnerID=HzOxMe3b&scp=85074274657&n=inward. Acesso em: 12 jan. 2023.BARROSA, R. C.Mauro SampaioCORREA, J. S.2022-01-122022-01-122019-08-12BARROSA, R. C.; SANPAIO, M.; CORREA, J. S. Impact of the inclusion of variable CO2 cost in the distribution network design. Production, v. 29, aug. 2019.0103-6513https://repositorio.fei.edu.br/handle/FEI/3745© 2019, Associacao Brasileira de Engenharia de Producao.Paper aims: This study aims to evaluate the economic-financial impact that the inclusion of environmental variable CO2 cost attributed to transportation (fuel consumption) and manufacturing activities (electricity consumption) represents in a distribution network optimization design. Originality: This is the first work carried out in Brazil to present a feasible eco-efficient distribution network in the technical and economic aspects considering the tax aspects of ICMS. In addition, this work addresses the inclusion of CO2 as a cost associated with transportation and manufacturing activities. Finally, for the first time in literature, a reference framework that considers environmental variables is presented. Research method: This study used the systematic literature review method to review the referential framework and carried out a cost reduction using specialist optimization software. Main findings: The technical and economical feasibility in achieving reduction of both total logistic and CO2 costs in a distribution network design in Brazil and the inexistence of trade-offs without technical solution to the eco-efficient configuration of the distribution network. Implications for theory and practice: The results of this paper presents a relevant contribution to logistics professionals and researchers, as it was able to present a framework and demonstrated the feasibility of an eco-efficient network design.Acesso AbertoImpact of the inclusion of variable CO2 cost in the distribution network designArtigo10.1590/0103-6513.20190065CO2 costDistribution network designEco-efficient distribution networkOptimizationStrategic decisions